T cells from patients with Candida sepsis display a suppressive immunophenotype
نویسندگان
چکیده
منابع مشابه
T cells from patients with Candida sepsis display a suppressive immunophenotype
BACKGROUND Despite appropriate therapy, Candida bloodstream infections are associated with a mortality rate of approximately 40%. In animal models, impaired immunity due to T cell exhaustion has been implicated in fungal sepsis mortality. The purpose of this study was to determine potential mechanisms of fungal-induced immunosuppression via immunophenotyping of circulating T lymphocytes from pa...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2015
ISSN: 1364-8535
DOI: 10.1186/s13054-016-1182-z